Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enrichment of minor allele of SNPs and genetic prediction of type 2 diabetes risk in British population.

PloS one - 1 Jan 2017

Lei Xiaoyun, Huang Shi

Abstract excerpt

Type 2 diabetes (T2D) is a complex disorder characterized by high blood sugar, insulin resistance, and relative lack of insulin. The collective effects of genome wide minor alleles of common SNPs, or the minor allele content (MAC) in an individual, have been linked with quantitative variations of complex traits and diseases. Here we studied MAC in T2D using previously published SNP datasets and found higher MAC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Diabetes Mellitus, Type 2
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Theoretical

Share to Polymorphism, Single Nucleotide

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 29099854
DOI: 10.1371/journal.pone.0187644
PMCID: PMC5669465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enrichment of minor allele of SNPs and genetic prediction of type 2 diabetes risk in British population.PMID 29099854Read ↗

Genetics of T2DM and Its Chronic Complications: Are We Any Closer to the Individual Prediction of Genetic Risk?Semantic proximity Read ↗

The genetic architecture of type 2 diabetes.Semantic proximity Read ↗

Improving type 2 diabetes polygenic risk scores by incorporating rare, low-frequency, and population-specific variantsSemantic proximity Read ↗

Susceptibility Loci for Type 2 Diabetes in the Ethnically Endogamous Indian Sindhi Population: A Pooled Blood Genome-Wide Association Study.Semantic proximity Read ↗

Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson's Disease.Semantic proximity Read ↗

Genomic risk score provides predictive performance for type 2 diabetes in the UK biobank.Semantic proximity Read ↗

Genome-wide polygenic risk score for type 2 diabetes in Indian population.Semantic proximity Read ↗

Evaluation of polygenic risk scores to differentiate between type 1 and type 2 diabetes.Semantic proximity Read ↗

Genetic Profiling and Early Detection of Type 2 Diabetes Subtypes through Sex-Stratified GWAS and Explainable AISemantic proximity Read ↗

Stratified genome-wide association analysis of type 2 diabetes reveals subgroups with genetic and environmental heterogeneity.Semantic proximity Read ↗

Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical HeterogeneitySemantic proximity Read ↗

Collective effects of common single nucleotide polymorphisms and genetic risk prediction in type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.