Population-Specific Differences in Pathogenic Variants of Genes Associated with Monogenic Parkinson’s Disease

Abstract excerpt

Background: Parkinson’s disease (PD) is a genetically complex neurodegenerative disorder. Up to 15% of cases are considered monogenic. However, research on monogenic PD has largely focused on populations of European ancestry, leaving gaps in our understanding of genetic variability in other populations. This study addresses this gap by analysing the allele frequencies of pathogenic and likely pathogenic variants...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Associations and Epidemiology
• Share to Genomics and Rare Diseases
• Share to Parkinson's Disease Mechanisms and Treatments