Article
Meta-analysis: IL28B polymorphisms predict sustained viral response in HCV patients treated with pegylated interferon-α and ribavirin.
Alimentary pharmacology & therapeutics - 1 Jul 2012
Chen Y, Xu H-X, Wang L-J, Liu X-X, Mahato R I, Zhao Y-R
Abstract excerpt
BACKGROUND: Interleukin (IL) 28B single nucleotide polymorphisms can predict sustained virological response (SVR) in hepatitis C virus (HCV) patients following pegylated interferon-alpha (PEG IFN-α) and ribavirin treatment. AIM: To design a meta-analysis to determine IL28B genotypes', rs12979860 CC and rs8099917 TT, correlation with SVR in PEG IFN-α/ribavirin-treated HCV patients. METHODS: Meta-analysis was...
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