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Article

Assessment of IL-28: rs12979860 and rs8099917 Polymorphisms in a Cohort of Cuban Chronic HCV Genotype 1b Patients.

Journal of biomolecular techniques : JBT - 1 Jul 2017

Palenzuela Gardón Daniel, Guillen Isabel Alicia, Fernández Julio R, Camacho Hamlet, Estevez Zurina Cinza, Dueñas Santiago, Alvares-Lajonchere Liz, Amador Yalena, Martinez-Donato Gillian, Han Junsong, Zhang Zhiming, Zhang Xiaona, Gao Yang, Campaña Juan Roca, Novoa Lidia I

Abstract excerpt

Hepatitis C virus (HCV) is a significant global public health problem with >185 million infections worldwide. A series of genome-wide association studies (GWAS) has identified IL-28B polymorphisms as a predictor of sustained virologic response (SVR), as well as spontaneous clearance in chronic HCV genotype 1 patients. The objective of this work was to evaluate the prevalence of IL-28B rs12979860 and rs8099917...

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Identifiers

PMID: 28058039
DOI: 10.7171/jbt.17-2801-001
PMCID: PMC5159608

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