Article
Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Oct 2010
Pineda Juan A, Caruz Antonio, Rivero Antonio, Neukam Karin, Salas Irene, Camacho Angela, Palomares José C, Mira José A, Martínez Antonio, Roldán Carmen, de la Torre Julián, Macías Juan
Abstract excerpt
BACKGROUND: Variation in the IL28B gene is associated with sustained virologic response (SVR) to pegylated interferon plus ribavirin in hepatitis C virus (HCV)-monoinfected patients with genotype 1. Data on other genotypes and on patients coinfected with human immunodeficiency virus (HIV) and HCV are more limited. We aimed to assess the predictive ability of variations in the single-nucleotide polymorphism...
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