Article
Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin.
Gastroenterology - 1 Jun 2010
McCarthy Jeanette J, Li Josephine H, Thompson Alexander, Suchindran Sunil, Lao Xiang Qian, Patel Keyur, Tillmann Hans L, Muir Andrew J, McHutchison John G
Abstract excerpt
BACKGROUND & AIMS: Patients with chronic hepatitis C virus (HCV) infections are treated with pegylated interferon and ribavirin (PEG-IFN/RBV), which is effective in less than 50% of those infected with HCV genotype 1. Genome-wide association studies have linked response to PEG-IFN/RBV with common...
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