Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synchronous endometrial/cervical and ovarian/fallopian tube carcinoma: a genome-wide mutation analysis.

The journal of pathology. Clinical research - 1 Sept 2025

Li Lihong, Yao Mengfei, Li Luyuan, Shi Susheng, Song Yan

Abstract excerpt

In this study, we explored the genomic underpinnings of synchronous endometrial and ovarian/fallopian tube carcinoma (SEOC) and synchronous cervical and ovarian/fallopian tube carcinoma (SCOC), focusing on their clonal relationships to discern whether these malignancies represent dual primary tumors (DPTs) or have metastatic origins. We established a cohort comprising 54 SEOC patients and 7 SCOC patients. After...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

Share to Exome Sequencing

Share to Fallopian Tube Neoplasms

Share to Neoplasms, Multiple Primary

Share to Ovarian Neoplasms

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 40760340
DOI: 10.1002/2056-4538.70040
PMCID: PMC12321604

Genes

SCOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synchronous endometrial/cervical and ovarian/fallopian tube carcinoma: a genome-wide mutation analysis.PMID 40760340Read ↗

Molecular profiling identifies synchronous endometrial and ovarian cancers as metastatic endometrial cancer with favorable clinical outcome.Semantic proximity Read ↗

Molecular evidence for a clonal relationship between synchronous uterine endometrioid carcinoma and ovarian clear cell carcinoma: a new example of "precursor escape"?Semantic proximity Read ↗

Next-Generation Sequencing of Tubal Intraepithelial Carcinomas.Semantic proximity Read ↗

High grade serous ovarian carcinomas originate in the fallopian tube.Semantic proximity Read ↗

Combination of Scoring Criteria and Whole Exome Sequencing Analysis of Synchronous Endometrial and Ovarian Carcinomas.Semantic proximity Read ↗

Evidence for lineage continuity between early serous proliferations (ESPs) in the Fallopian tube and disseminated high-grade serous carcinomas.Semantic proximity Read ↗

Elucidating the pathogenesis of synchronous and metachronous tumors in a woman with endometrioid carcinomas using a whole-exome sequencing approach.Semantic proximity Read ↗

Genomic landscape and evolutionary trajectories of ovarian cancer precursor lesions.Semantic proximity Read ↗

The molecular origin and taxonomy of mucinous ovarian carcinomaSemantic proximity Read ↗

A Subset of Serous Tubal Intraepithelial Carcinoma (STIC)-Like Lesions and Concurrent High-Grade Endometrial Carcinoma Are Genomically Related Entities.Semantic proximity Read ↗

Rete Ovarii Epithelial Cells as an Unappreciated Cell of Origin for Pelvic and Ovarian High-Grade Serous CarcinomaSemantic proximity Read ↗

Synchronous endometrioid endometrial and ovarian carcinomas are biologically related: A clinico‑pathological and molecular (next generation sequencing) study of 22�casesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.