Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes.

G3 (Bethesda, Md.) - 14 Jul 2015

Kofoed Megan, Milbury Karissa L, Chiang Jennifer H, Sinha Sunita, Ben-Aroya Shay, Giaever Guri, Nislow Corey, Hieter Philip, Stirling Peter C

Abstract excerpt

Systematic analyses of essential gene function using mutant collections in Saccharomyces cerevisiae have been conducted using collections of heterozygous diploids, promoter shut-off alleles, through alleles with destabilized mRNA, destabilized protein, or bearing mutations that lead to a temperature-sensitive (ts) phenotype. We previously described a method for construction of barcoded ts alleles in a systematic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diploidy
Share to DNA Barcoding, Taxonomic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Essential

Share to High-Throughput Nucleotide Sequencing

Share to Protein Conformation

Share to Saccharomyces cerevisiae Proteins

Share to Temperature

Share to Yeasts

Source

Open in PubMed Open full text

Identifiers

PMID: 26175450
DOI: 10.1534/g3.115.019174
PMCID: PMC4555224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes.PMID 26175450Read ↗

Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae.Semantic proximity Read ↗

Systematic exploration of essential yeast gene function with temperature-sensitive mutants.Semantic proximity Read ↗

Exploration of essential gene functions via titratable promoter alleles.Semantic proximity Read ↗

Mutant power: using mutant allele collections for yeast functional genomics.Semantic proximity Read ↗

A high-efficiency method to replace essential genes with mutant alleles in yeast.Semantic proximity Read ↗

Diverse natural variants suppress mutations in hundreds of essential genesSemantic proximity Read ↗

Natural variants suppress mutations in hundreds of essential genes.Semantic proximity Read ↗

PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

The modifiers that cause changes in gene essentialitySemantic proximity Read ↗

Screen for temperature-sensitive mutants of non-essential yeast genes.Semantic proximity Read ↗

A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.Semantic proximity Read ↗

Global analysis of the yeast knock-out phenomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.