Article
PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae.
Nucleic acids research - 1 Jan 2012
Jin Ke, Li Jingjing, Vizeacoumar Frederick S, Li Zhijian, Min Renqiang, Zamparo Lee, Vizeacoumar Franco J, Datti Alessandro, Andrews Brenda, Boone Charles, Zhang Zhaolei
Abstract excerpt
About one-fifth of the genes in the budding yeast are essential for haploid viability and cannot be functionally assessed using standard genetic approaches such as gene deletion. To facilitate genetic analysis of essential genes, we and others have assembled collections of yeast strains expressing temperature-sensitive (ts) alleles of essential genes. To explore the phenotypes caused by essential gene mutation we...
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