A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.

doi:10.1038/nmeth.1234

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.

Nature methods - 1 Aug 2008

Breslow David K, Cameron Dale M, Collins Sean R, Schuldiner Maya, Stewart-Ornstein Jacob, Newman Heather W, Braun Sigurd, Madhani Hiten D, Krogan Nevan J, Weissman Jonathan S

Abstract excerpt

Functional genomic studies in Saccharomyces cerevisiae have contributed enormously to our understanding of cellular processes. Their full potential, however, has been hampered by the limited availability of reagents to systematically study essential genes and the inability to quantify the small e...

Topics

Alleles
Databases, Nucleic Acid
Flow Cytometry
Gene Deletion
Genetic Techniques
Genome, Fungal
Proteasome Endopeptidase Complex
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 18622397
DOI: 10.1038/nmeth.1234
PMCID: PMC2756093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-18622397-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics