Article
Associations of common copy number variants in glutathione S-transferase mu 1 and D-dopachrome tautomerase-like protein genes with risk of schizophrenia in a Japanese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2015
Nakamura Toru, Ohnuma Tohru, Hanzawa Ryo, Takebayashi Yuto, Takeda Mayu, Nishimon Shohei, Sannohe Takahiro, Katsuta Narimasa, Higashiyama Ryoko, Shibata Nobuto, Arai Heii
Abstract excerpt
Oxidative-stress, genetic regions of interest (1p13 and 22q11), and common copy number variations (CNVs) may play roles in the pathophysiology of schizophrenia. In the present study, we confirmed associations between schizophrenia and the common CNVs in the glutathione (GSH)-related genes GSTT1, DDTL, and GSTM1 using quantitative real-time polymerase chain reaction analyses of 620 patients with schizophrenia and...
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