Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia.

doi:10.1002/ajmg.b.32426

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Article

Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2016

Higashiyama Ryoko, Ohnuma Tohru, Takebayashi Yuto, Hanzawa Ryo, Shibata Nobuto, Yamamori Hidenaga, Yasuda Yuka, Kushima Itaru, Aleksic Branko, Kondo Kenji, Ikeda Masashi, Hashimoto Ryota, Iwata Nakao, Ozaki Norio, Arai Heii

Abstract excerpt

Chromosome 22q11.2 deletion syndrome and genetic variations including single-nucleotide polymorphism (SNP) and copy number variation (CNV) in catechol-O-methyltransferase (COMT) situated at 22q11.2 remains controversial. Here, the genetic relationship between COMT and Japanese patients with schizophrenia was investigated by examining whether the SNPs correlated with schizophrenia based on a common disease-common...

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Identifiers

PMID: 26852906
DOI: 10.1002/ajmg.b.32426

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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