Article
No association between glutathione-synthesis-related genes and Japanese schizophrenia.
Psychiatry and clinical neurosciences - 1 Feb 2011
Hanzawa Ryo, Ohnuma Tohru, Nagai Yasuhito, Shibata Nobuto, Maeshima Hitoshi, Baba Hajime, Hatano Tokiko, Takebayashi Yuto, Hotta Yuri, Kitazawa Maiko, Arai Heii
Abstract excerpt
AIMS: Schizophrenia is a major psychiatric disorder with complex genetic, environmental, and psychological causes, and oxidative stress may be involved in the pathogenesis of the disease. Glutathione (GSH), one of the main cellular non-protein antioxidants and redox regulators, and altered GSH levels have been reported in various regions in patients with schizophrenia. Three enzymes are responsible for GSH...
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