Article
Copy-number variation genotyping of GSTT1 and GSTM1 gene deletions by real-time PCR.
Clinical chemistry - 1 Sept 2009
Rose-Zerilli Matthew J, Barton Sheila J, Henderson A John, Shaheen Seif O, Holloway John W
Abstract excerpt
BACKGROUND: Structural variation in the human genome is increasingly recognized as being highly prevalent and having relevance to common human diseases. Array-based comparative genome-hybridization technology can be used to determine copy-number variation (CNV) across entire genomes, and quantitative PCR (qPCR) can be used to validate de novo variation or assays of common CNV in disease-association studies....
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