Article
Genetic polymorphism of glutathione S-transferase T1: a candidate genetic modifier of individual susceptibility to schizophrenia.
Psychiatry research - 30 Sept 2007
Saadat Mostafa, Mobayen Fatemeh, Farrashbandi Hassan
Abstract excerpt
Schizophrenia is highly heritable, but the specific genes involved remain to be determined. A genome wide scan approach has indicated that human chromosome 22q11.2 potentially influences schizophrenia susceptibility. The gene encoding glutathione S-transferase T1 (GSTT1), which pertains to phase II biotransformation enzymes, was also mapped to the above-mentioned band. The present case-control study was performed...
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