Article
Copy number variation in schizophrenia in the Japanese population.
Biological psychiatry - 1 Feb 2010
Ikeda Masashi, Aleksic Branko, Kirov George, Kinoshita Yoko, Yamanouchi Yoshio, Kitajima Tsuyoshi, Kawashima Kunihiro, Okochi Tomo, Kishi Taro, Zaharieva Irina, Owen Michael J, O'Donovan Michael C, Ozaki Norio, Iwata Nakao
Abstract excerpt
BACKGROUND: Copy number variants (CNVs) have been shown to increase the risk to develop schizophrenia. The best supported findings are at 1q21.1, 15q11.2, 15q13.3, and 22q11.2 and deletions at the gene neurexin 1 (NRXN1). METHODS: In this study, we used Affymetrix 5.0 arrays to investigate the role of rare CNVs in 575 patients with schizophrenia and 564 control subjects from Japan. RESULTS: There was a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.