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Article

High-throughput genotyping of copy number variation in glutathione S-transferases M1 and T1 using real-time PCR in 20,687 individuals.

Clinical biochemistry - 1 Feb 2009

Nørskov Marianne S, Frikke-Schmidt Ruth, Loft Steffen, Tybjaerg-Hansen Anne

Abstract excerpt

OBJECTIVES: Characteristic for the genes encoding glutathione S-transferase (GST) M1 and GSTT1 is a null allele, suggested to increase susceptibility to chronic diseases. We report an optimized method for the determination of copy number variation (CNV) in GST genes. DESIGN AND METHODS: Real-time multiplex PCR reactions were optimized for quantification of GSTM1 and GSTT1 CNV using the DeltaCt method, a fixed...

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Identifiers

PMID: 19026998
DOI: 10.1016/j.clinbiochem.2008.10.020

Genes

GSTT1
GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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