Article
Association study between glutathione S-transferase GST-M1, GST-T1, and GST-P1 polymorphisms and tardive dyskinesia.
Human psychopharmacology - 1 Jan 2009
Kang Seung-Gul, Lee Heon-Jeong, Choi Jung-Eun, An Hyonggin, Rhee MinKyu, Kim Leen
Abstract excerpt
OBJECTIVES: Data from several studies suggest that oxidative stress may play a role in the pathophysiology of tardive dyskinesia (TD). Glutathione S-transferase (GST) enzymes play important roles in protecting cells against oxidative stress. In the present study, we investigated the hypothesis that polymorphisms in genes for these detoxifying enzymes can influence susceptibility to TD in patients with...
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