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Article

Gene expression in colon cancer: A focus on tumor site and molecular phenotype

14 Jul 2015

Abstract excerpt

Hundreds to thousands of genes are differentially expressed in tumors when compared to nontumor colonic tissue samples. We evaluated gene expression patterns to better understand differences in colon cancer by tumor site and tumor molecular phenotype. We analyzed RNA-seq data from tumor/normal paired samples from 175 colon cancer patients. We implemented a cross validation strategy with nonparametric tests to...

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PMID: 26171582
DOI: 10.1002/gcc.22265

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