Article
MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype.
Genes, chromosomes & cancer - 1 Mar 2011
Slattery Martha L, Wolff Erica, Hoffman Michael D, Pellatt Daniel F, Milash Brett, Wolff Roger K
Abstract excerpt
MicroRNAs are thought to have an impact on cell proliferation, apoptosis, stress responses, maintenance of stem cell potency, and metabolism and are, therefore, important in the carcinogenic process. In this study, we examined 40 colon tumors, 30 rectal tumors, and 30 normal tissue samples (10 proximal colon, 10 distal colon, and 10 rectal paired with cancer cases) to examine miRNA expression profiles in colon...
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