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Toward a comprehensive and systematic methylome signature in colorectal cancers

31 Jul 2013

Abstract excerpt

CpG Island Methylator Phenotype (CIMP) is one of the underlying mechanisms in colorectal cancer (CRC). This study aimed to define a methylome signature in CRC through a methylation microarray analysis and a compilation of promising CIMP markers from the literature. Illumina HumanMethylation27 (IHM27) array data was generated and analyzed based on statistical differences in methylation data (1st approach) or based...

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Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 23975090
DOI: 10.4161/epi.25497

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