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Article

Improved survival among colon cancer patients with increased differentially expressed pathways

7 Apr 2015

Abstract excerpt

BACKGROUND: Studies of colorectal cancer (CRC) have shown that hundreds to thousands of genes are differentially expressed in tumors when compared to normal tissue samples. In this study, we evaluate how genes that are differentially expressed in colon versus normal tissue influence survival. METHODS: We performed RNA-seq on tumor/normal paired samples from 175 colon cancer patients. We implemented a cross...

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PMID: 25890236
DOI: 10.1186/s12916-015-0292-9

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