Article
Colorectal tumor molecular phenotype and miRNA: expression profiles and prognosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2016
Slattery Martha L, Herrick Jennifer S, Mullany Lila E, Wolff Erica, Hoffman Michael D, Pellatt Daniel F, Stevens John R, Wolff Roger K
Abstract excerpt
MiRNAs regulate gene expression by post-transcriptionally suppressing mRNA translation or by causing mRNA degradation. It has been proposed that unique miRNAs influence specific tumor molecular phenotype. In this paper, we test the hypotheses that miRNA expression differs by tumor molecular pheno...
Topics
- Adult
- Aged
- Biomarkers, Tumor
- California
- Case-Control Studies
- Colorectal Neoplasms
- Computational Biology
- DNA Methylation
- DNA Mutational Analysis
- Female
- Gene Expression Profiling
- Genetic Predisposition to Disease
- Humans
- Male