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Article

Identification of multiple genetic loci linked to the propensity for "behavioral despair" in mice.

Genome research - 1 Mar 2002

Yoshikawa Takeo, Watanabe Akiko, Ishitsuka Yuichi, Nakaya Akihiro, Nakatani Noriaki

Abstract excerpt

The forced swim test (FST) and tail suspension test (TST) are widely used and well established screening paradigms for antidepressants. A variety of antidepressive agents are known to reduce immobility time in both FST and TST. To identify genetic determinants of immobility duration in both tests, we analyzed 560 F2 mice from an intercross between C57BL/6 (B6) and C3H/He (C3) strains. Composite interval mapping...

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Source

Identifiers

PMID: 11875023
DOI: 10.1101/gr.222602

Genes

TST
FST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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