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Article

Major Depression-Associated NEGR1 Gene is Modulated in Stress-Susceptible Male Mice.

Frontiers in bioscience (Landmark edition) - 19 Mar 2026

Mingardi Jessica, Salluzzo Marco, Rimondini Roberto, Musazzi Laura, Carboni Lucia

Abstract excerpt

BACKGROUND: Neuronal growth regulator 1 (NEGR1) is an IgLON cell adhesion molecule significantly associated with depression risk in genome-wide association studies. Since the role of NEGR1 in depression pathophysiology remains incompletely understood, we investigated changes in NEGR1-associated gene expression levels in stress-susceptible male mice exposed to chronic restraint stress. METHODS: Mice were subjected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 2

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Source

Identifiers

PMID: 41914288
DOI: 10.31083/FBL49360

Genes

NEGR1
ADAM10
LSAMP
FGFR2
NTM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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