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Article

Genetic dissection of the tail suspension test: a mouse model of stress vulnerability and antidepressant response.

Biological psychiatry - 1 Jul 2007

Liu Xiaoqing, Stancliffe Devin, Lee Samuel, Mathur Shelly, Gershenfeld Howard K

Abstract excerpt

BACKGROUND: The tail suspension test (TST) is a mouse screening test for antidepressants. METHODS: An F2 intercross was derived from NMRI and 129S6 inbred strains (n = 747). Mice underwent standardized TST with 2 sessions: (1) baseline and (2) imipramine (30 mg/kg, intraperitoneally) TST. RESULTS: A whole genome scan of this intercross mapped significant basal TST quantitative trait loci (QTL) on chromosomes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17125744
DOI: 10.1016/j.biopsych.2006.08.017

Genes

TST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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