Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2010

Miller Brooke H, Schultz Laura E, Long Bradley C, Pletcher Mathew T

Abstract excerpt

The Tail Suspension Test (TST), which measures behavioral despair, is widely used as an animal model of human depressive disorders and antidepressant efficacy. In order to identify novel genes involved in the regulation of TST performance, we crossed an inbred strain exhibiting low immobility in the TST (RIIIS/J) with two high-immobility strains (C57BL/6J and NZB/BlNJ) to create two distinct F2 hybrid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminopyridines
Share to Behavior, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Depression

Share to Hindlimb Suspension

Share to Mice, Inbred NZB

Share to Receptors, GABA-A

Share to Thiophenes

Source

Open in PubMed Open full text

Identifiers

PMID: 20512339
DOI: 10.1007/s00335-010-9266-6
PMCID: PMC2890984

Genes

TST
GABRA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.PMID 20512339Read ↗

Identification of multiple genetic loci linked to the propensity for "behavioral despair" in mice.Semantic proximity Read ↗

Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety.Semantic proximity Read ↗

Identification of multiple genetic loci in the mouse controlling immobility time in the tail suspension and forced swimming tests.Semantic proximity Read ↗

Genetic dissection of the tail suspension test: a mouse model of stress vulnerability and antidepressant response.Semantic proximity Read ↗

Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping.Semantic proximity Read ↗

[Approach to depressogenic genes from genetic analyses of animal models].Semantic proximity Read ↗

Affective and cognitive effects of global deletion of alpha3-containing gamma-aminobutyric acid-A receptors.Semantic proximity Read ↗

Gabra2 is a genetic modifier of Dravet syndrome in mice.Semantic proximity Read ↗

Identification of quantitative trait Loci that affect aggressive behavior in mice.Semantic proximity Read ↗

Major Depression-Associated NEGR1 Gene is Modulated in Stress-Susceptible Male Mice.Semantic proximity Read ↗

Evidence of association between gamma-aminobutyric acid type A receptor genes located on 5q34 and female patients with mood disorders.Semantic proximity Read ↗

Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.