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Article

Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety.

PloS one - 29 Dec 2010

Miller Brooke H, Schultz Laura E, Gulati Anisha, Su Andrew I, Pletcher Mathew T

Abstract excerpt

BACKGROUND: Animal models of human behavioral endophenotypes, such as the Tail Suspension Test (TST) and the Open Field assay (OF), have proven to be essential tools in revealing the genetics and mechanisms of psychiatric diseases. As in the human disorders they model, the measurements generated in these behavioral assays are significantly impacted by the genetic background of the animals tested. In order to...

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Identifiers

PMID: 21206921
DOI: 10.1371/journal.pone.0014458
PMCID: PMC3012073

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TST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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