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Article

The effect of Young's modulus on the neuronal differentiation of mouse embryonic stem cells.

Acta biomaterialia - 1 Oct 2015

Ali Shahzad, Wall Ivan B, Mason Chris, Pelling Andrew E, Veraitch Farlan S

Abstract excerpt

There is substantial evidence that cells produce a diverse response to changes in ECM stiffness depending on their identity. Our aim was to understand how stiffness impacts neuronal differentiation of embryonic stem cells (ESC's), and how this varies at three specific stages of the differentiation process. In this investigation, three effects of stiffness on cells were considered; attachment, expansion and...

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Identifiers

PMID: 26159105
DOI: 10.1016/j.actbio.2015.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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