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Article

Role of Mechanical Cues in Cell Differentiation and Proliferation: A 3D Numerical Model.

PloS one - 1 Jan 2015

Mousavi Seyed Jamaleddin, Doweidar Mohamed Hamdy

Abstract excerpt

Cell differentiation, proliferation and migration are essential processes in tissue regeneration. Experimental evidence confirms that cell differentiation or proliferation can be regulated according to the extracellular matrix stiffness. For instance, mesenchymal stem cells (MSCs) can differentiate to neuroblast, chondrocyte or osteoblast within matrices mimicking the stiffness of their native substrate. However,...

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Identifiers

PMID: 25933372
DOI: 10.1371/journal.pone.0124529
PMCID: PMC4416758

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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