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Article

Influence of substrate stiffness on the phenotype of heart cells.

Biotechnology and bioengineering - 15 Apr 2010

Bhana Bashir, Iyer Rohin K, Chen Wen Li Kelly, Zhao Ruogang, Sider Krista L, Likhitpanichkul Morakot, Simmons Craig A, Radisic Milica

Abstract excerpt

Adult cardiomyocytes (CM) retain little capacity to regenerate, which motivates efforts to engineer heart tissues that can emulate the functional and mechanical properties of native myocardium. Although the effects of matrix stiffness on individual CM have been explored, less attention was devoted to studies at the monolayer and the tissue level. The purpose of this study was to characterize the influence of...

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Source

Identifiers

PMID: 20014437
DOI: 10.1002/bit.22647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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