Article
Sequence variants of the aging gene CISD2 and the risk for Alzheimer's disease.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jul 2015
Hsieh Ching-Jow, Weng Pei-Hsuan, Chen Jen-Hau, Chen Ta-Fu, Sun Yu, Wen Li-Li, Yip Ping-Keung, Chu Yi-Min, Chen Yen-Ching
Abstract excerpt
BACKGROUND/PURPOSE: The CISD2 gene has been related to life span control and mitochondrial dysfunction in animals. In addition, inhibition of mitochondrial enzymes due to an accumulation of beta-amyloid peptide has been related to Alzheimer's disease (AD). This study aimed to explore the association between sequence variants of the CISD2 gene and risk for AD, which has not been explored previously. METHODS: This...
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