Article
A polymorphism in SOD2 is associated with development of Alzheimer's disease.
Genes, brain, and behavior - 1 Nov 2007
Wiener H W, Perry R T, Chen Z, Harrell L E, Go R C P
Abstract excerpt
Genes involved in cellular mechanisms to repair oxidative damage are strong candidates as etiologic factors for Alzheimer's disease (AD). One important enzyme involved in this mechanism is superoxide dismutase 2 (SOD2). The gene for this enzyme lies within a single haplotype block at 6q25.3, a re...
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