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Article

Correlation Between SIRT2 3'UTR Gene Polymorphism and the Susceptibility to Alzheimer's Disease.

Journal of molecular neuroscience : MN - 1 Jun 2020

Shen Yuanyuan, Chen Liyu, Zhang Shuijing, Xie Liquan

Abstract excerpt

The purpose of this study is to investigate the correlation between single-nucleotide polymorphism (SNP) at the 3' end of the untranslated region (UTR) of Sirtuin 2 (SIRT2) gene and the risk of developing Alzheimer's disease (AD), and to explore its underlying mechanisms. In total, 260 patients with AD and 260 healthy controls were recruited in this study. The genotype of rs2015 and rs2241703 loci of the SIRT2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Alzheimer Disease

Polymorphism, Single Nucleotide

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PMID: 32124252
DOI: 10.1007/s12031-020-01513-y

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