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Article

Association analysis of genetic polymorphisms in the CDC2 gene with late-onset Alzheimer disease.

Dementia and geriatric cognitive disorders - 1 Jan 2007

Liang Xueying, Schnetz-Boutaud Nathalie, Bartlett Jackie, Anderson Brent M, Gwirtsman Harry, Schmechel Don, Carney Regina, Gilbert John R, Pericak-Vance Margaret A, Haines Jonathan L

Abstract excerpt

BACKGROUND: Alzheimer disease (AD) is a complex neurodegenerative disorder resulting from multiple genetic and non-genetic factors. Linkage studies indicated that chromosome 10 has at least one locus for this disease. The cell division cycle 2 (CDC2) gene, which is close to one of the linkage regions, has previously been associated with the risk of AD with an odds ratio of 1.78. Biologically, CDC2, which is...

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PMID: 17159347
DOI: 10.1159/000097857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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