Article
Association between DCHS2 gene and mild cognitive impairment and Alzheimer's disease in an elderly Brazilian sample.
International journal of geriatric psychiatry - 1 Dec 2016
Vieira Renalice Neves, Ávila Rafaela, de Paula Jonas Jardim, Cintra Marco Túlio Gualberto, de Souza Renan Pedra, Nicolato Rodrigo, Malloy-Diniz Leandro, de Miranda Débora Marques, de Moraes Edgar Nunes, de Marco Luiz Armando, Romano-Silva Marco Aurélio, Bicalho Maria Aparecida Camargos
Abstract excerpt
OBJECTIVES: In 2012, Kamboh and colleagues published a genome-wide association study that identified the DCHS2 gene (rs1466662 T/A) influencing the age at onset of Alzheimer's disease (AD). We aimed to investigate if there is association between the DCHS2 gene and amnestic mild cognitive impairment (aMCI) and AD in a sample of the Brazilian population. METHODS: 143 controls, 79 aMCI and 299 AD patients were...
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