Article
Genetic polymorphisms of a novel vascular susceptibility gene, Ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer's disease.
PloS one - 1 Jan 2011
Lin Kun-Pei, Chen Shih-Yuan, Lai Liang-Chuan, Huang Yi-Ling, Chen Jen-Hau, Chen Ta-Fu, Sun Yu, Wen Li-Li, Yip Ping-Keung, Chu Yi-Min, Chen Wei J, Chen Yen-Ching
Abstract excerpt
BACKGROUND: Accumulated evidences have shown that vascular risk factors, e.g., hypertension, diabetes mellitus and hyperlipidemia, may be related to the risk of dementia. This study investigated the association between genetic polymorphisms of a vascular susceptibility gene, Ninjurin2 (NINJ2), and the risk of dementia, which has not been explored previously. METHODS: A total of 275 Alzheimer's disease (AD)...
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