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Article

The human ATF1 rs11169571 polymorphism increases essential hypertension risk through modifying miRNA binding.

FEBS letters - 22 Jul 2015

Yang Sibao, Gao Yongjian, Liu Guohui, Li Jiayu, Shi Kaiyao, Du Beibei, Si Daoyuan, Yang Ping

Abstract excerpt

Activating transcription factor 1 (ATF1) may be involved in essential hypertension (EH) by induction of NADPH oxidase 1 (NOX1) and radical oxygen species (ROSs) production. Abnormal expression of ATF1 was found in EH in previous microarray analysis. Here we tested whether a single nucleotide polymorphism (SNP) located in the 3'-untranslated region (3'UTR) of ATF1 was associated with EH susceptibility by affecting...

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Source

Identifiers

PMID: 26149214
DOI: 10.1016/j.febslet.2015.06.029

Genes

ATF1
NOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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