Article
Haplotype-based case-control study of the human AGTR1 gene and essential hypertension in Han Chinese subjects.
Clinical biochemistry - 1 Feb 2010
Nie Sheng-jie, Wen-ru Tang, Bi-feng Chen, Jin Li, Wen Zhang, Sheng-jun Luo, Wei-wei Li, Hai-jing Yu, Chun-jie Xiao
Abstract excerpt
OBJECTIVES: Essential hypertension is considered to be a multifactorial trait resulting from the combined influence of environmental and genetic determinants. The aim of the study is to assess the association between the human AGTR1 gene and essential hypertension (EH) using a haplotype-based case-control study in Han Chinese subjects. DESIGN AND METHODS: Seven tag SNPs and the A1166C polymorphism of the AGTR1...
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