Article

The secret of VDAC isoforms is in their gene regulation? Characterization of human VDAC genes expression profile, promoter activity, and transcriptional regulators

2020-08-10

Abstract excerpt

<h4>Background</h4> VDACs (Voltage-Dependent Anion-selective Channels) are pore-forming proteins of the outer mitochondrial membrane, whose permeability is primarily due to their presence. In higher eukaryotes three isoforms raised during the evolution: they have the same exon-intron organization and the proteins show the same channel-forming activity. We provide a comprehensive analysis of the three human VDAC g...

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Literature Corpus work: 638ac8de-cd8d-534f-af38-944ddf962634
DOI: 10.1101/2020.08.10.244327

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