The Hypertension Risk Variant Rs820430 Functions as an Enhancer of SLC4A7.

doi:10.1093/ajh/hpw127

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The Hypertension Risk Variant Rs820430 Functions as an Enhancer of SLC4A7.

American journal of hypertension - 1 Feb 2017

Wang Laiyuan, Li Hongfan, Yang Bin, Guo Liwei, Han Xikun, Li Lin, Li Mengting, Huang Jianfeng, Gu Dongfeng

Abstract excerpt

BACKGROUND: The large-scale meta-analysis of genome-wide association study (GWAS) recently identified a genomic locus where the genetic variant at rs820430 was strongly associated with hypertension in Chinese Han population, with its T allele conferred increased risks. However, the biological and disease-relevant mechanisms for this association remain elusive. METHODS: A group of 275 participants from rural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrophoresis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HEK293 Cells

Share to Hypertension

Share to Population Surveillance

Share to Real-Time Polymerase Chain Reaction

Share to Rural Population

Share to Sodium-Bicarbonate Symporters

Share to Survival Rate

Source

Open in PubMed

Identifiers

PMID: 27784683
DOI: 10.1093/ajh/hpw127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Hypertension Risk Variant Rs820430 Functions as an Enhancer of SLC4A7.PMID 27784683Read ↗

Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study.Semantic proximity Read ↗

A functional SNP rs12718466 in APOA1 promoter modulates gene expression via interaction with SOX7.Semantic proximity Read ↗

Genetic susceptibility analysis of FGF5 polymorphism to preeclampsia in Chinese Han population.Semantic proximity Read ↗

Significant association between upstream transcription factor 1 rs2516839 polymorphism and hepatocellular carcinoma risk: a case-control study.Semantic proximity Read ↗

Genetic regulatory and biological implications of the 10q24.32 schizophrenia risk locus.Semantic proximity Read ↗

FOXA1 of regulatory variant associated with risk of breast cancer through allele-specific enhancer in the Chinese population.Semantic proximity Read ↗

The common single-nucleotide polymorphism rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women.Semantic proximity Read ↗

Polymorphisms in the long non-coding RNA CDKN2B-AS1 may contribute to higher systolic blood pressure levels in hypertensive patients.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the 5' upstream region of the C4BPA gene with essential hypertension in a northeastern Han Chinese population.Semantic proximity Read ↗

Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population.Semantic proximity Read ↗

[Association between CACNB2 gene polymorphisms and essential hypertension].Semantic proximity Read ↗

Functional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.