Conditional mutagenesis strategies in zebrafish.

doi:10.1016/j.tig.2022.04.007

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Article

Conditional mutagenesis strategies in zebrafish.

Trends in genetics : TIG - 1 Aug 2022

Kalvaitytė Miglė, Balciunas Darius

Abstract excerpt

Gene disruption or knockout is an essential tool for elucidating gene function. Conditional knockout methodology was developed to further advance these studies by enabling gene disruption at a predefined time and/or in discrete cells. While the conditional knockout method is widely used in the mouse, technical limitations have stifled direct adoption of this methodology in other animal models including the...

Topics

Alleles
Animals
Gene Editing
Mice
Mutagenesis
Phenotype
Zebrafish

Source

Open in PubMed

Identifiers

PMID: 35662532
DOI: 10.1016/j.tig.2022.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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