PNPLA3 genetic variants determine hepatic steatosis in non-obese chronic hepatitis C patients.

doi:10.1038/srep11901

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Article

PNPLA3 genetic variants determine hepatic steatosis in non-obese chronic hepatitis C patients.

Scientific reports - 3 Jul 2015

Huang Chung-Feng, Chen Jyh-Jou, Yeh Ming-Lun, Huang Ching-I, Hsieh Ming-Yen, Yang Hua-Ling, Dai Chia-Yen, Huang Jee-Fu, Lin Zu-Yau, Chen Shinn-Cherng, Chuang Wan-Long, Chen Yao-Li, Yu Ming-Lung

Abstract excerpt

The influence of patatin-like phospholipase domain-containing 3 (PNPLA3) genetic variants in the development of liver steatosis in Asian chronic hepatitis C patients remains elusive. A total of 1018 biopsy-proven chronic hepatitis C patients were enrolled for evaluation. The proportions of PNPLA3 rs738409 GG genotype carriage were 7.8% (44/563), 15.8% (58/367) and 19.3% (17/88) in patients with no (liver fat...

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PMID: 26139292
DOI: 10.1038/srep11901
PMCID: PMC4490397

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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