Article
The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C.
BMC infectious diseases - 19 Dec 2017
Manchiero Caroline, Nunes Arielle Karen da Silva, Magri Mariana Carvalheiro, Dantas Bianca Peixoto, Mazza Celso Carmo, Barone Antonio Alci, Tengan Fátima Mitiko
Abstract excerpt
BACKGROUND: Prospective studies have shown that 80% of acute hepatitis C virus (HCV) cases progress to chronic infection; approximately 10-20% of patients with these conditions will develop liver cirrhosis within 2 to 3 decades, and 1-5% will develop liver cancer. Some studies have indicated that the rs738409 polymorphism of the PNPLA3 gene is associated with steatosis and the progression of advanced fibrosis....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.