Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B.

doi:10.1002/hep.26445

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Article

Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B.

Hepatology (Baltimore, Md.) - 1 Oct 2013

Viganò Mauro, Valenti Luca, Lampertico Pietro, Facchetti Floriana, Motta Benedetta Maria, D'Ambrosio Roberta, Romagnoli Solange, Dongiovanni Paola, Donati Benedetta, Fargion Silvia, Colombo Massimo

Abstract excerpt

UNLABELLED: Steatosis is a common histopathological feature of chronic hepatitis B (CHB) and has been associated with severity of liver disease. Recently, the rs738409 I148M patatin-like phospholipase domain-containing 3 (PNPLA3) polymorphism has been demonstrated to influence steatosis susceptibility and fibrosis progression in patients with different liver diseases, but no data are yet available for CHB. The...

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PMID: 23564580
DOI: 10.1002/hep.26445

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PNPLA3

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