Article
PNPLA3 rs1010023 Predisposes Chronic Hepatitis B to Hepatic Steatosis but Improves Insulin Resistance and Glucose Metabolism.
Journal of diabetes research - 1 Jan 2017
Pan Qin, Chen Mei-Mei, Zhang Rui-Nan, Wang Yu-Qin, Zheng Rui-Dan, Mi Yu-Qiang, Liu Wen-Bin, Shen Feng, Su Qing, Fan Jian-Gao
Abstract excerpt
PNPLA3 polymorphisms serve as the genetic basis of hepatic steatosis in normal population and lead to dysregulated glucose metabolism. Whether it underlies the hepatic steatosis and glucose homeostasis in chronic hepatitis B patients remains uncertain. Here, we investigated the PNPLA3 polymorphisms in biopsy-proven chronic hepatitis B patients with (CHB+HS group, n = 52) or without hepatic steatosis (CHB group, n...
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