Article
HIV population genotypic tropism testing and its clinical significance.
Current opinion in HIV and AIDS - 1 Sept 2012
Obermeier Martin, Symons Jori, Wensing Annemarie M J
Abstract excerpt
PURPOSE OF REVIEW: HIV co-receptor tropism testing is recommended before therapy when the C-C chemokine receptor type 5 antagonist maraviroc is initiated. This review addresses the use of population genotypic tropism testing in relation to clinical practice. RECENT FINDINGS: Genotypic tropism tests predict viral co-receptor tropism based on the sequence of the V3 loop of the viral envelope. HIV occurs in a swarm...
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