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Article

DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.

Photochemistry and photobiology - 1 Jan 2000

Paul-Konietzko Katja, Thomale Juergen, Arakawa Hiroshi, Iliakis George

Abstract excerpt

In eukaryotic cells helix-distorting DNA lesions like cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine-pyrimidone photoproducts (6-4 PPs) are efficiently removed by nucleotide excision repair (NER). NER is a multistep process where in the end, subsequent to replication over the gap, the remaining nick is sealed by a DNA ligase. Lig1 has been implicated as the major DNA ligase in NER. Recently, Lig3 has...

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PMID: 26131740
DOI: 10.1111/php.12487

Genes

CPD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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