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Article

An efficiency analysis of high-order combinations of gene-gene interactions using multifactor-dimensionality reduction.

BMC genomics - 1 Jul 2015

Yang Cheng-Hong, Lin Yu-Da, Yang Cheng-San, Chuang Li-Yeh

Abstract excerpt

BACKGROUND: Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of genes to determine the complex relationship between diseases and polymorphisms in humans. However, the astronomical number of high-order combinations makes MDR a highly time-consuming process which can be difficult to implement for multiple tests to identify more complex interactions between genes. This study proposes...

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Identifiers

PMID: 26126977
DOI: 10.1186/s12864-015-1717-8
PMCID: PMC4487567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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