Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computational analysis of gene-gene interactions using multifactor dimensionality reduction.

Expert review of molecular diagnostics - 1 Nov 2004

Moore Jason H

Abstract excerpt

Understanding the relationship between DNA sequence variations and biologic traits is expected to improve the diagnosis, prevention and treatment of common human diseases. Success in characterizing genetic architecture will depend on our ability to address nonlinearities in the genotype-to-phenotype mapping relationship as a result of gene-gene interactions, or epistasis. This review addresses the challenges...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Diagnosis, Computer-Assisted
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Software

Source

Identifiers

PMID: 15525222
DOI: 10.1586/14737159.4.6.795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computational analysis of gene-gene interactions using multifactor dimensionality reduction.PMID 15525222Read ↗

Epistasis, complexity, and multifactor dimensionality reduction.Semantic proximity Read ↗

Bioinformatics approaches for detecting gene-gene and gene-environment interactions in studies of human disease.Semantic proximity Read ↗

Epistasis analysis using multifactor dimensionality reduction.Semantic proximity Read ↗

Model-Based Multifactor Dimensionality Reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data.Semantic proximity Read ↗

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions.Semantic proximity Read ↗

Class Balanced Multifactor Dimensionality Reduction to Detect Gene-Gene Interactions.Semantic proximity Read ↗

A Bayesian method for identifying genetic interactions.Semantic proximity Read ↗

Dimensionality reduction approach for many-objective epistasis analysis.Semantic proximity Read ↗

Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions.Semantic proximity Read ↗

Multiobjective differential evolution-based multifactor dimensionality reduction for detecting gene-gene interactions.Semantic proximity Read ↗

A multifactorial dimensionality reduction model for gene polymorphisms and environmental interaction analysis for the detection of susceptibility for type 2 diabetic and cardiovascular diseasesSemantic proximity Read ↗

Exhaustive Variant Interaction Analysis using Multifactor Dimensionality ReductionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.